TRUB1 Antibody (Center) [APR31015G]

TRUB1 Antibody (Center) [APR31015G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This TRUB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the Central region of human TRUB1.

Cellular Localisation: Nucleus. Cytoplasm, cytosol. Note=Catalyzes pseudouridylation of mRNAs in the nucleus.

Molecular Weight: 37253

Clone: Polyclonal

Gene Name: TRUB1 {ECO:0000303|PubMed:12736709, ECO:0000312|HGNC:HGNC:16060}

Gene ID: 142940

Function: Pseudouridine synthase that catalyzes pseudouridylation of mRNAs (PubMed:28073919) . Mediates pseudouridylation of mRNAs with the consensus sequence 5'-GUUCNANNC-3', harboring a stem-loop structure (PubMed:28073919) . Constitutes the major pseudouridine synthase acting on mRNAs (PubMed:28073919) .

Summary: Tissue Location: Highly expressed in heart, skeletal muscle and liver. Expressed at lower levels in lung, small intestine, kidney and spleen.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P

Dilution: WB--1:1000 IHC-P--1:100~500

Synonyms: Probable tRNA pseudouridine synthase 1, 5499-, TRUB1, PUS4