TSHB polyclonal Antibody | BS8434

TSHB polyclonal Antibody | BS8434 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB IHC IF

Application Range: WB: 1:500~1:2000 IHC/IF: 1:50~1:200

Background: Various hormones are secreted from the anterior pituitary during development and growth, including thyroid-stimulating hormone (TSH, also known as thyrotropin), follicle-stimulating hormone (FSH) and leutinizing hormone (LH) . TSH, FSH, and LH are heterodimers formed from a common α chain and a unique β chain. TSH is a glycoprotein involved in the control of thyroid structure and metabolism, which stimulates the release of the thyroid hormones. TSHβ is regulated by thyroid hormone (T3) and various retinoid compounds. TSHβ binds to the thyroid-stimulating hormone receptor (TSHR), which plays a major role in regulating thyroid function. TSHR is thought to exist in multiple glycosylation states. The third cytoplasmic loop of TSHR has been identified as critical for its role in regulating inositol phosphate and cAMP formation.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: TSHB polyclonal Antibody detects endogenous levels of TSHB protein.

Molecular Weight: ~ 16 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Thyrotropin subunit beta; Thyroid-stimulating hormone subunit beta; TSH-B; TSH-beta; Thyrotropin beta chain; INN: Thyrotropin alfa; TSHB

Immunogen: Recombinant full length Human TSHB.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: