TSHR Antibody (Center) [APR33031G]

TSHR Antibody (Center) [APR33031G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: M

Specificity: This TSHR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 217-252 amino acids from the Central region of human TSHR.

Cellular Localisation: Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein

Molecular Weight: 86830

Clone: Polyclonal

Gene Name: TSHR

Gene ID: 7253

Function: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin (PubMed:11847099, PubMed:12045258) . Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin (PubMed:12045258) . The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed:11847099) . Plays a central role in controlling thyroid cell metabolism (By similarity) .

Summary: Tissue Location: Expressed in thyroide cells (at protein level) (PubMed:11847099) . Expressed in the thyroid (PubMed:2610690)

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Thyrotropin receptor, Thyroid-stimulating hormone receptor, TSH-R, TSHR, LGR3