TTL monoclonal Antibody | MB65527

TTL monoclonal Antibody | MB65527 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: WB

Application Range: WB 1:500

Background: TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529) . Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]) . [supplied by OMIM]. COMPLETENESS: complete on the 3' end.

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: tubulin tyrosine ligase

Molecular Weight: 43.0 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: MGC46235

Immunogen: Full length human recombinant protein of human TTL (NP_714923) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A