TTNPB | 2776

TTNPB is a highly potent retinoic acid receptor (RAR) agonist (EC₅₀ = 21 nM, 4.0 nM, and 2.4 nM for RARα, RARβ, and RARγ, respectively). Enhances reprogramming efficiency in chemically induced pluripotent stem cells (CiPSCs).

TTNPB is a highly potent retinoic acid receptor (RAR) agonist (EC₅₀ = 21 nM, 4.0 nM, and 2.4 nM for RARα, RARβ, and RARγ, respectively). Enhances reprogramming efficiency in chemically induced pluripotent stem cells (CiPSCs).

2776 | TTNPB DataSheet

Alternate Name/Synonyms: 4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acid; Ro 13-7410

Appearance: White solid

Formulation: N/A

CAS Number: 71441-28-6

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₄H₂₈O₂

Molecular Weight: 348.48

Cell-Permeable?: Y

Purity: ≥98%

Solubilities: DMSO (~8 mg/ml) or EtOH (~ 3 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A highly potent retinoic acid receptor (RAR) agonist

MDL Number: MFCD00673917

PubChem CID: 5289501

SMILES: CC(=CC1=CC=C(C=C1)C(=O)O)C2=CC3=C(C=C2)C(CCC3(C)C)(C)C

InChi: InChI=1S/C24H28O2/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-20-21(15-19)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14+

InChi Key: FOIVPCKZDPCJJY-JQIJEIRASA-N