TTP-22 | B2565

TTP-22 is a potent casein kinase 2 (CK2) inhibitor with an IC₅₀ value of 100 nM (Ki = 40 nM). It displays selectivity for CK2 over JNK3, ROCK1, and MET with no inhibitory effects towards these kinases even at 10 μM.

TTP-22 is a potent casein kinase 2 (CK2) inhibitor with an IC₅₀ value of 100 nM (Ki = 40 nM). It displays selectivity for CK2 over JNK3, ROCK1, and MET with no inhibitory effects towards these kinases even at 10 μM.

B2565 | TTP-22 DataSheet

Alternate Name/Synonyms: 3-[[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]thio]-propanoic acid, TTP22, TTP 22

Appearance: Crystalline solid

Formulation:

CAS Number: 329907-28-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₆H₁₄N₂O₂S₂

Molecular Weight: 330.4

Cell-Permeable?: True

Purity: ≥98% by HPLC

Solubilities: ~10 mg/ml in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A casein kinase 2 (CK2) inhibitor

MDL Number:

PubChem CID: 1536915

SMILES: CC(C=C1)=CC=C1C2=CSC3=NC=NC(SCCC(O)=O)=C32

InChi: InChI=1S/C16H14N2O2S2/c1-10-2-4-11(5-3-10)12-8-22-16-14(12)15(17-9-18-16)21-7-6-13(19)20/h2-5,8-9H,6-7H2,1H3,(H,19,20)

InChi Key: RAOULLCLLOGTDA-UHFFFAOYSA-N