TTR Polyclonal Antibody | E-AB-18211

TTR Polyclonal Antibody | E-AB-18211 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Amyloid polyneuropathy, Amyloidosis I, ATTR, Carpal tunnel syndrome 1, CTS, CTS1, Dysprealbuminemic euthyroidal hyperthyroxinemia, Dystransthyretinemic hyperthyroxinemia, Epididymis luminal protein 111, HEL111, HsT2651, PALB, Prealbumin amyloidosis type I, Prealbumin, Prealbumin Thyroxine-binding, Senile systemic amyloidosis, TBPA, Thyroxine binding prealbumin, Transthyretin, TTHY, TTR, TTR protein

Application: WB, IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Neuroscience

Background: Transthyretin (TTR) is a plasma transport protein for thyroxine and retinol, through the association with retinol-binding protein. It is a homotetrameric protein synthesized mainly in liver, choroid plexus, retinal pigment epithelium, and pancreas.Within the CNS, TTR is the only known protein synthesized solely by the choroid plexus. Mutant and wildtype TTR give rise to various forms of amyloid deposition (amyloidosis). Defects in TTR are the cause of amyloidosis transthyretin-related (AMYL-TTR), hyperthyroxinemia dystransthyretinemic euthyroidal (HTDE) and carpal tunnel syndrome type 1 (CTS1). In addition, positive immunostaining for TTR has been reported as a sensitive diagnostic marker of choroid plexus tumors. (22103483)

Concentration: 0.72 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human TTR

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 16 kDa

Molecular Weight(Observed): Refer to figures