BW
Tubulin γ (F414) polyclonal Antibody | BS1483
- SKU:
- BW-BS1483
- Availability:
- Usually ships in 5 working days
Description
Tubulin γ (F414) polyclonal Antibody | BS1483 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: IHC
Application Range: IHC: 1:50~1:200
Background: TUB4, the gene for Saccharomyces cerevisiae γ-Tubulin, encodes a 473 amino acid structural protein that localizes to the spindle pole body. γ Tubulin, an essential protein for cell growth, organizes microtubule arrays in the nucleus and cytoplasm. γ Tubulin-depleted cells fail to form functional spindles and arrest during nuclear division. γ Tubulin associates with spindle body components Spc97 and Spc98 to form the γ Tubulin complex. The budding yeast γ Tubulin complex contains one molecule each of Spc97 and Spc98 and two molecules of γ Tubulin. In the SPB, Spc110 binds Spc97 and Spc98 of the γ Tubulin complex. 2D gel analysis indicates five isoforms of γ Tubulin. The phosphorylation of γ Tubulin at Tyr 445 plays a regulatory role in microtubule formation. The incidence rate for this phosphorylation event peaks during G1.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Tubulin γ (F414) polyclonal Antibody detects endogenous levels of Tubulin γ protein.
Molecular Weight: ~ 51 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Tubulin gamma-1 chain; Gamma-1-tubulin; Gamma-tubulin complex component 1; GCP-1; TUBG1; TUBG; Tubulin γ1; Tubulin-γ1; Tubulinγ1
Immunogen: Synthetic peptide, corresponding to amino acids 380-430 of Human Tubulin γ.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: