Tubulin γ polyclonal Antibody | BS71930

Tubulin γ polyclonal Antibody | BS71930 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB 1:500 - 1:2000

Background: TUB4, the gene for Saccharomyces cerevisiae γ-Tubulin, encodes a 473 amino acid structural protein that localizes to the spindle pole body. γ Tubulin, an essential protein for cell growth, organizes microtubule arrays in the nucleus and cytoplasm. γ Tubulin-depleted cells fail to form functional spindles and arrest during nuclear division. γ Tubulin associates with spindle body components Spc97 and Spc98 to form the γ Tubulin complex. The budding yeast γ Tubulin complex contains one molecule each of Spc97 and Spc98 and two molecules of γ Tubulin. In the SPB, Spc110 binds Spc97 and Spc98 of the γ Tubulin complex. 2D gel analysis indicates five isoforms of γ Tubulin. The phosphorylation of γ Tubulin at Tyr 445 plays a regulatory role in microtubule formation. The incidence rate for this phosphorylation event peaks during G1.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Tubulin γ polyclonal Antibody detects endogenous levels of Tubulin γ protein.

Molecular Weight: 51kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Tubulin gamma-1 chain; Gamma-1-tubulin; Gamma-tubulin complex component 1; GCP-1; TUBG1; TUBG; Tubulin γ1; Tubulin-γ1; Tubulinγ1

Immunogen: Recombinant protein of human TUBG1

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: