TWEAKR polyclonal Antibody | BS91387

TWEAKR polyclonal Antibody | BS91387 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Application: ICC IHC FC

Application Range: ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100

Background: Fn14, the TWEAK receptor, is a recently identified member of the TNF receptor superfamily and is expressed on smooth muscle cells and endothelial cells. It is a weak inducer of apoptosis and promotes angiogenesis. Fn14 is a type 1 membrane protein. It associates with TRAF1 and TRAF2, and may modulate cellular adhesion to matrix proteins. Fn14 is highly expressed in heart, placenta and kidney, and moderately expressed in lung, skeletal muscle and pancreas. It is the smallest member of the TNF receptor (TNFR) superfamily described to date, and signals via recruitment of several different TNFR-associated factors.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: TWEAKR polyclonal Antibody detects endogenous levels of TWEAKR protein.

Molecular Weight: 14 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: FGF-inducible 14, TweakR, TNFRSF12A, FN14, CD 266, CD266, CD266 antigen, FGF inducible 14, FGF-inducible 14, Fibroblast growth factor inducible immediate early response protein 14, Fibroblast growth factor-inducible immediate-early response protein 14, FN 14, FN14, TNFRSF 12A, TNFRSF12A, TNR12, Tumor necrosis factor receptor superfamily member 12A, TWEAK R, Tweak receptor, Tweak-receptor, TweakR,

Immunogen: Synthetic peptide within human TWEAKR aa 80-120.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Peptide affinity purified.

Pathway: