TX1-85-1 | B1313

TX1-85-1 is the first selective Her3 (ErbB3) ligand. TX1-85-1 forms a covalent bond with Cys721 located in the ATP-binding site of Her3.

TX1-85-1 is the first selective Her3 (ErbB3) ligand. TX1-85-1 forms a covalent bond with Cys721 located in the ATP-binding site of Her3.

B1313 | TX1-85-1 DataSheet

Alternate Name/Synonyms: N-(5-(1-(4-(4-Acetylpiperazin-1-yl)cyclohexyl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-phenoxyphenyl)acrylamide

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1603845-32-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₂H₃₆N₈O₃

Molecular Weight: 580.69

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: The first selective Her3 (ErbB3) ligand

MDL Number: N/A

PubChem CID: 78243752

SMILES: CC(=O)N1CCN(CC1)C2CCC(CC2)N3C4=C(C(=N3)C5=CC(=C(C=C5)OC6=CC=CC=C6)NC(=O)C=C)C(=NC=N4)N

InChi: InChI=1S/C32H36N8O3/c1-3-28(42)36-26-19-22(9-14-27(26)43-25-7-5-4-6-8-25)30-29-31(33)34-20-35-32(29)40(37-30)24-12-10-23(11-13-24)39-17-15-38(16-18-39)21(2)41/h3-9,14,19-20,23-24H,1,10-13,15-18H2,2H3,(H,36,42)(H2,33,34,35)

InChi Key: FYICDSWKKFSYOM-UHFFFAOYSA-N