UBA7 Polyclonal Antibody | E-AB-52436

UBA7 Polyclonal Antibody | E-AB-52436 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: D8, MGC12713, UBA1, ubiquitin activating enzyme E1 homolog B, UBA1B, UBA7, UBA7, ubiquitin activating enzyme E1, UBA7, Ube 1L, UBE 2, UBE1L, UBE2, Ubiquitin activating enzyme 2, Ubiquitin activating enzyme E1 homolog, Ubiquitin Activating Enzyme E1 Like, Ubiquitin activating enzyme E1 related protein, Ubiquitin-activating enzyme 7, Ubiquitin-activating enzyme E1 homolog, ubiquitin-activating enzyme-2, ubiquitin-like modifier activating enzyme 7, Ubiquitin-like modifier-activating enzyme 7

Application: IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.

Concentration: 0.6 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human UBA7

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A