UBAP2L Antibody | 8371

UBAP2L Antibody | 8371 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: UBAP2L antibody was raised against a 19 amino acid peptide from near the amino terminus of human UBAP2L.
The immunogen is located within amino acids 200 - 250 of UBAP2L.

Research Area: Stem Cell

Tested Application: E, WB, ICC, IF

Application: UBAP2L antibody can be used for the detection of UBAP2L by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunocytochemistry at 10 μg/ml.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: UBAP2L antibody is human and mouse reactive. At least four isoforms of UBAP2L are known to exist; this antibody will detect all four isoforms. This antibody is predicted to not cross-react with UBAP2.

Positive Control 1: Cat. No. 1201 - HeLa Cell Lysate

Positive Control 2: Cat. No. 17-001 - HeLa Cell Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 120 kDa
Observed: 130 kDa

Validation: N/A

Isoform: N/A

Purification: UBAP2L Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: UBAP2L Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: UBAP2L antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: Ubiquitin associated protein 2-like, NICE-4

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The UBA domain-containing protein ubiquitin associated protein 2-like (UBAP2L) , also known as NICE4, is a ubiquitously expressed 1, 087 amino acid protein. UBAP2L is preferentially expressed in hematopoietic stem cell (HSC) populations and interacts with BMI1, a well-known determinant of HSC function (1) . It is essential for the activity of long-term repopulating HSCs but not the BMI1-dependent repression of the Ink4a/Arf locus (1) .