UBCS-039 | B2759

UBCS-039 is the first synthetic SIRT6 activator (EC50 = 38 μM); induces a time-dependent activation of autophagy in several human tumor cell lines. UBCS-039 induces deacetylation of SIRT6-targeted histone H3 sites in human cancer cells.

UBCS-039 is the first synthetic SIRT6 activator (EC50 = 38 μM); induces a time-dependent activation of autophagy in several human tumor cell lines. UBCS-039 induces deacetylation of SIRT6-targeted histone H3 sites in human cancer cells.

B2759 | UBCS-039 DataSheet

Alternate Name/Synonyms: MC-3154,UBCS039,4-Pyridin-3-yl-4,5-dihydro-pyrrolo[1,2-a]quinoxaline,MC3154

Appearance: Crystalline solid

Formulation:

CAS Number: 358721-70-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₆H₁₃N₃

Molecular Weight: 247.29

Cell-Permeable?: TRUE

Purity: ≥98%

Solubilities: >60 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: The first synthetic SIRT6 activator

MDL Number:

PubChem CID: 2803797

SMILES: C1=CC=C2C(=C1)NC(C3=CC=CN32)C4=CN=CC=C4

InChi: InChI=1S/C16H13N3/c1-2-7-14-13(6-1)18-16(12-5-3-9-17-11-12)15-8-4-10-19(14)15/h1-11,16,18H

InChi Key: BSOBGTYXYGHUTD-UHFFFAOYSA-N