Description
UBCS-039 is the first synthetic SIRT6 activator (EC50 = 38 μM); induces a time-dependent activation of autophagy in several human tumor cell lines. UBCS-039 induces deacetylation of SIRT6-targeted histone H3 sites in human cancer cells.
UBCS-039 is the first synthetic SIRT6 activator (EC50 = 38 μM); induces a time-dependent activation of autophagy in several human tumor cell lines. UBCS-039 induces deacetylation of SIRT6-targeted histone H3 sites in human cancer cells.
Alternate Name/Synonyms: MC-3154,UBCS039,4-Pyridin-3-yl-4,5-dihydro-pyrrolo[1,2-a]quinoxaline,MC3154
Appearance: Crystalline solid
Formulation:
CAS Number: 358721-70-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₆H₁₃N₃
Molecular Weight: 247.29
Cell-Permeable?: TRUE
Purity: ≥98%
Solubilities: >60 mg/ml DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: The first synthetic SIRT6 activator
MDL Number:
PubChem CID: 2803797
SMILES: C1=CC=C2C(=C1)NC(C3=CC=CN32)C4=CN=CC=C4
InChi: InChI=1S/C16H13N3/c1-2-7-14-13(6-1)18-16(12-5-3-9-17-11-12)15-8-4-10-19(14)15/h1-11,16,18H
InChi Key: BSOBGTYXYGHUTD-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |