UBE2D2 monoclonal Antibody | MB65570

UBE2D2 monoclonal Antibody | MB65570 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: IHC, WB

Application Range: WB 1:2000, IHC 1:150

Background: Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub) -proteasome system (UPS) . An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5) . Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: ubiquitin conjugating enzyme E2 D2

Molecular Weight: 16.6 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: E2 (17) KB2; PUBC1; UBC4; UBC4/5; UBCH4; UBCH5B

Immunogen: Full length human recombinant protein of human UBE2D2 (NP_003330) produced in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A