UBIAD1 Antibody | 7751

UBIAD1 Antibody | 7751 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: Predicted species reactivity based on immunogen sequence: Chicken: (87%)

Immunogen: UBIAD1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human UBIAD1.
The immunogen is located within amino acids 210 - 260 of UBIAD1.

Research Area: Homeostasis

Tested Application: E, WB, IHC-P, IF

Application: UBIAD1 antibody can be used for detection of UBIAD1 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry at 5 μg/mL. For Immunoflorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Specificiy: UBIAD1 antibody is human, mouse and rat reactive.

Positive Control 1: Cat. No. 1404 - Mouse Liver Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 37 kDa
Observed: 45 kDa

Validation: N/A

Isoform: N/A

Purification: UBIAD1 antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: UBIAD1 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: UBIAD1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: UBIAD1 Antibody: SCCD, TERE1, UbiA prenyltransferase domain-containing protein 1, Transitional epithelial response protein 1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The UbiA prenyltransferase domain containing 1 (UBIAD1) protein, also known as TERE1, was initially identified as a down-regulated gene in transitional cell carcinoma of the bladder (1) . Recently it has been shown to bind the cholesterol carrier APOE and modulate cellular cholesterol levels (2) . Mutations in the UBIAD1 gene can cause Schnyder crystalline corneal dystrophy, an autosomal dominant disease characterized by progressive opacification of the cornea resulting from the local accumulation of lipids (3) .