UBQLN1 Polyclonal Antibody | E-AB-65316

UBQLN1 Polyclonal Antibody | E-AB-65316 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: UBQLN1, DA41, DSK2, PLIC-1, UBQN, XDRP1

Application: WB

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology

Background: This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human UBQLN1 (NP_038466.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:200-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 18 kDa/43 kDa/59 kDa/62 kDa

Molecular Weight(Observed): 70 kDa