UBXN1 Polyclonal Antibody | E-AB-18676

UBXN1 Polyclonal Antibody | E-AB-18676 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 2B28, 4930455J02Rik, D19Ertd721e, MGC124706, MGC6696, mY33K, Protein 2B28, RGD1309471, SAKS1, SAPK substrate protein 1, T25529, UBA/UBX 33.3 kDa protein, UBX domain containing protein 1, UBX domain protein 1, UBXD10, UBXN1

Application: WB, IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cell Biology, Signal transduction

Background: Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.

Concentration: 1.2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Full length fusion protein

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 33 kDa

Molecular Weight(Observed): Refer to figures