UchL1 Antibody [13C4] | 33-222

UchL1 Antibody [13C4] | 33-222 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Bovine, Dog, Guinea pig, Human, Mouse, Pig, Rabbit, Rat, Sheep, Zebrafish

Homology: N/A

Immunogen: Native protein from brain was used as the immunogen for this UchL1 antibody.

Research Area: Cell Cycle, Neuroscience

Tested Application: WB, IF

Application: WB: 0.5-1 ug/ml
IF: 1-2 ug/ml
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the UchL1 antibody to be titered up or down for optimal performance.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: Protein G affinity chromatography

Clonality: Monoclonal

Clone: 13C4

Isotype: IgG2a, kappa

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide

Concentration: 0.2 mg/mL

Storage Condition: Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.

Alternate Name: Ubiquitin carboxyl-terminal hydrolase isozyme L1, UCH-L1, 6---, Neuron cytoplasmic protein 95, PGP 95, PGP95, Ubiquitin thioesterase L1, UCHL1

User Note: Optimal dilutions for each application to be determined by the researcher

BACKGROUND: This antibody specifically reacts with a protein of 20-30kDa, identified as UchL1 (Ubiquitin carboxyl-terminal hydrolase-1) , or PGP9.5. Studies using UchL1 antibody have shown that expression is related to tumor progression, with high expression correlating with poor prognosis, making the protein a potentially useful marker for pancreatic and invasive colorectal cancer. A mutation in gene is believed to cause a form of Parkinson's disease.