UFC1 Antibody (N-term) [APR04469G]

UFC1 Antibody (N-term) [APR04469G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This UFC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-31 amino acids from the N-terminal region of human UFC1.

Cellular Localisation: N/A

Molecular Weight: 19458

Clone: Polyclonal

Gene Name: UFC1 {ECO:0000303|PubMed:15071506, ECO:0000312|HGNC:HGNC:26941}

Gene ID: 51506

Function: E1-like enzyme which specifically catalyzes the second step in ufmylation (PubMed:15071506, PubMed:29868776) . Accepts the ubiquitin-like modifier UFM1 from the E1 enzyme UBA5 and forms an intermediate with UFM1 via a thioester linkage (PubMed:15071506, PubMed:29868776) . Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress (PubMed:32160526) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Ubiquitin-fold modifier-conjugating enzyme 1, Ufm1-conjugating enzyme 1, UFC1