UK-371804 | B1843

UK-371804 is a potent urokinase-type plasminogen activator (uPA) inhibitor with a Ki of 10 nM. Displays 4000-fold selectivity vs tPA and 2700-fold vs plasmin.

UK-371804 is a potent urokinase-type plasminogen activator (uPA) inhibitor with a Ki of 10 nM. Displays 4000-fold selectivity vs tPA and 2700-fold vs plasmin.

B1843 | UK-371804 DataSheet

Alternate Name/Synonyms: 2-((4-chloro-1-((diaminomethylene)amino)isoquinoline)-7-sulfonamido)-2-methylpropanoic acid

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 256477-09-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₁₄H₁₆ClN₅O₄S

Molecular Weight: 385.82

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent urokinase-type plasminogen activator (uPA) inhibitor

MDL Number: N/A

PubChem CID: 9952109

SMILES: CC(C)(C(=O)O)NS(=O)(=O)C1=CC2=C(C=C1)C(=CN=C2N=C(N)N)Cl

InChi: InChI=1S/C14H16ClN5O4S/c1-14(2,12(21)22)20-25(23,24)7-3-4-8-9(5-7)11(19-13(16)17)18-6-10(8)15/h3-6,20H,1-2H3,(H,21,22)(H4,16,17,18,19)

InChi Key: XSDAXWRCPTYNOD-UHFFFAOYSA-N