UMPS Polyclonal Antibody | E-AB-18508

UMPS Polyclonal Antibody | E-AB-18508 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: ODC, OMPdecase, OPRT, OPRTase, Orotate phosphoribosyl transferase and orotidine 5' decarboxylase, Orotate phosphoribosyltransferase, Orotate phosphoribosyltransferase phosphoribosyltransferase, Orotidine 5' phosphate decarboxylase, Orotidine 5''-phosphate decarboxylase, RP11-71H17.9, UMP synthase, Umps, UMPS, Uridine 5' monophosphate synthase, Uridine monophosphate synthetase

Application: IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Epigenetics and Nuclear Signaling, Metabolism

Background: This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.

Concentration: 0.6 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human UMPS

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A