UNC-3866 | B2361

UNC-3866 is a potent and selective antagonist of CBX4 and CBX7 chromodomains with (Kd ≈ 100 nM). It is 6- to 63-fold selective for these chromodomains over the other CBX and CDY chromodomains.

UNC-3866 is a potent and selective antagonist of CBX4 and CBX7 chromodomains with (Kd ≈ 100 nM). It is 6- to 63-fold selective for these chromodomains over the other CBX and CDY chromodomains.

B2361 | UNC-3866 DataSheet

Alternate Name/Synonyms: N-[4-(1,1-dimethylethyl)benzoyl]-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-L-serine, methyl ester,UNC3866

Appearance: Crystalline solid

Formulation:

CAS Number: 1872382-47-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₄₃H₆₆N₆O₈

Molecular Weight: 795.04

Cell-Permeable?: TRUE

Purity: ≥98%

Solubilities: DMSO in 0

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A potent and selective antagonist of CBX4 and CBX7 chromodomains

MDL Number:

PubChem CID: 101000000

SMILES: CCN(CC)CCCCC(C(=O)NC(CO)C(=O)OC)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=CC=C(C=C2)C(C)(C)C

InChi: InChI=1S/C43H66N6O8/c1-10-49(11-2)24-16-15-19-33(39(53)48-36(27-50)42(56)57-9)45-41(55)34(25-28(3)4)46-37(51)29(5)44-40(54)35(26-30-17-13-12-14-18-30)47-38(52)31-20-22-32(23-21-31)43(6,7)8/h12-14,17-18,20-23,28-29,33-36,50H,10-11,15-16,19,24-27H2,1-9H3,(H,44,54)(H,45,55)(H,46,51)(H,47,52)(H,48,53)/t29-,33-,34-,35-,36-/m0/s1

InChi Key: UMRRDXVUROEIKJ-JCXBGQGISA-N