UNC-926, free base | B2158

UNC-926 is a methyl-lysine (Kme) reader domain inhibitor; it binds to the MBT domain of the L3MBTL1 protein (Kd = 3.9 μM). Selectively inhibits the L3MBTL13XMBT-H4K20me1 interaction in a peptide pull down assay.

UNC-926 is a methyl-lysine (Kme) reader domain inhibitor; it binds to the MBT domain of the L3MBTL1 protein (Kd = 3.9 μM). Selectively inhibits the L3MBTL13XMBT-H4K20me1 interaction in a peptide pull down assay.

B2158 | UNC-926, free base DataSheet

Alternate Name/Synonyms: (3-Bromophenyl)[4-(1-pyrrolidinyl)-1-piperidinyl]methanone

Appearance: Cystalline solid

Formulation: N/A

CAS Number: 1184136-10-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₆H₂₁BrN₂O

Molecular Weight: 337.26

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A methyl-lysine (Kme) reader domain inhibitor

MDL Number: N/A

PubChem CID: 61041645

SMILES: C1CCN(C1)C2CCN(CC2)C(=O)C3=CC(=CC=C3)Br

InChi: InChI=1S/C16H21BrN2O/c17-14-5-3-4-13(12-14)16(20)19-10-6-15(7-11-19)18-8-1-2-9-18/h3-5,12,15H,1-2,6-11H2

InChi Key: OWGLFIKZKQOYHZ-UHFFFAOYSA-N