UQCRC1 polyclonal Antibody | BS70539

UQCRC1 polyclonal Antibody | BS70539 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Monkey

Application: WB IHC

Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200

Background: UQCRC1, or Ubiquinol-cytochrome-c reductase complex core protein 1, is a core subunit of the mitochondrial respiratory complex III. It is the largest nuclear encoded subunit of the complex. UQCRC1 plays a key role in mitochondria-to-nucleus retrograde response and is involved in the mitochondrial proton gradient formation. It has also shown to interact with Nogo, an inhibitor of neurite growth after spinal cord injury. UQCRC1 has been found at high expression levels in breast and ovarian tumors, positively correlating with Cox-2 expression. Transcription of UQCRC1 is repressed by the nuclear protein methyl-CpG-binding protein-2 (MeCP2) .

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: UQCRC1 polyclonal Antibody detects endogenous levels of UQCRC1 protein.

Molecular Weight: ~ 53 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: QCR1; UQCR1; D3S3191;

Immunogen: Recombinant protein of human UQCRC1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: