USH1C Antibody | 19-353

USH1C Antibody | 19-353 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of zebrafish USH1C (NP_001035018.1) .

Research Area: Apoptosis, Cell Cycle, Neuroscience

Tested Application: WB, IHC

Application: WB: 1:200 - 1:2000
IHC: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: HT-29

Positive Control 2: Mouse kidney

Positive Control 3: Mouse small intestine

Positive Control 4: Rat testis

Positive Control 5: Rat kidney

Positive Control 6: N/A

Molecular Weight: Observed: 73kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: zgc:136806, harmonin, Usher syndrome 1C (autosomal recessive, severe) , harmonin pseudogene

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a scaffold protein that functions in the assembly of Usher protein complexes. The protein contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST degradation sequence. Defects in this gene are the cause of Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18. Multiple transcript variants encoding different isoforms have been found for this gene.