USP19 polyclonal Antibody | BS5975

USP19 polyclonal Antibody | BS5975 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. Ubiquitin-specific-processing protease 19 (USP19), also known as ubiquitin carboxyl-terminal hydrolase 19, ubiquitin thioesterase 19 and deubiquitinating enzyme 19, is a 1318 amino acid member of the peptidase C19 family of proteins. USP19 is thought to be involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome. Four known isoforms of USP19 exist as a result of alternative splicing events.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: USP19 polyclonal Antibody detects endogenous levels of USP19 protein.

Molecular Weight: ~ 146 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Ubiquitin carboxyl-terminal hydrolase 19; Deubiquitinating enzyme 19; Ubiquitin thioesterase 19; Ubiquitin-specific-processing protease 19; Zinc finger MYND domain-containing protein 9; USP19; KIAA0891; ZMYND9

Immunogen: Synthetic peptide, corresponding to amino acids 439-484 of Human USP19.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: