USP2 Polyclonal Antibody | E-AB-10878

USP2 Polyclonal Antibody | E-AB-10878 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 41 kDa ubiquitin specific protease, 41 kDa ubiquitin-specific protease, Deubiquitinating enzyme 2, Ubiquitin carboxyl terminal hydrolase 2, Ubiquitin carboxyl-terminal hydrolase 2, ubiquitin specific peptidase 2, Ubiquitin specific processing protease 2, Ubiquitin specific protease 12, Ubiquitin specific protease 9, Ubiquitin specific protease, 41kD, Ubiquitin thioesterase 2, Ubiquitin thiolesterase 2, Ubiquitin-specific-processing protease 2, Ubiquitin-specific-processing protease testis, UBP-t, UBP2, UBP41, USP2, USP9

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cell Biology, Epigenetics and Nuclear Signaling

Background: This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Concentration: 0.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human USP2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A