BW
USP6NL polyclonal Antibody | BS61476
- SKU:
- BW-BS61476
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- Usually ships in 5 working days
Description
USP6NL polyclonal Antibody | BS61476 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB
Application Range: WB: 1:500~1:1000
Background: GTPase-activating proteins (GAPs) accelerate the intrinsicrate of GTP hydroysis of Ras-related proteins, resulting in downregulation of their active form.RN-tre (related to the N-terminus of tre), also known as USP6NL (USP6 Nterminal like) or TRE2NL, is an 828 amino acid protein thatcontains one RabGAP TBC domain. Expressed in awide variety of tissues, RN-tre functions as a GTPase-activating protein for Rab 5A and isthought to be involved in receptor trafficking, aswell asin the inhibition of EGFR internalization. In response to DNA damage, RN-tre may be phosphorylated by ATM or ATR. The gene encoding RN-tre mapsto human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: USP6NL polyclonal Antibody detects endogenous levels of USP6NL protein.
Molecular Weight: ~ 86 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: USP6 N-terminal-like protein; Related to the N-terminus of tre; RN-tre; USP6NL; KIAA0019
Immunogen: Synthetic peptide, corresponding to amino acids 446-491 of Human USP6NL.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: