VCP Polyclonal Antibody | E-AB-18489

VCP Polyclonal Antibody | E-AB-18489 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 15S Mg(2+) ATPase p97 subunit, 15S Mg(2+)-ATPase p97 subunit, ALS14, ATPase p97, CDC48, IBMPFD, MGC131997, MGC148092, MGC8560, p97, TER ATPase, TERA, TERA, Transitional endoplasmic reticulum ATPase, Valosin containing protein, Valosin-containing protein, VCP, Yeast Cdc48p homolog

Application: WB, IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Metabolism, Neuroscience, Signal Transduction

Background: VCP(Valosin-containing protein) belongs to the AAA ATPase family.VCP was first identified as a result of attempts to clone a putative peptide hormone called valosin. It was found that the cloned cDNA encoded a ubiquitously expressed 90 kDa cytosolic protein, termed VCP, which showed none of the characteristics of a peptide hormone precursor.Defects in VCP are the cause of inclusion body myopathy with early-onset Paget disease and frontotemporal dementia (IBMPFD) and amyotrophic lateral sclerosis type 14 with or without frontotemporal dementia (ALS14)

Concentration: 0.5 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human VCP

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 89 kDa

Molecular Weight(Observed): Refer to figures