VEGFR1 polyclonal Antibody | BS91435

VEGFR1 polyclonal Antibody | BS91435 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, mouse, rat

Application: WB IHC

Application Range: WB:1:1,000 IHC:1:200

Background: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. Vascular endothelial growth factor receptor 1 is a protein that in humans is encoded by the FLT1 gene. Oncogene FLT belongs to the src gene family and is related to oncogene ROS. Like other members of this family, it shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. The sequence structure of the FLT gene resembles that of the FMS gene; hence, Yoshida et al. (1987) proposed the name FLT as an acronym for FMS-like tyrosine kinase. FLT1 has been shown to interact with PLCG1 and vascular endothelial growth factor B (VEGF-B) .

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: VEGFR1 polyclonal Antibody detects endogenous levels of VEGFR1 protein.

Molecular Weight: 150 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: VEGFR-1, FLT-1, FLT, EC 2.7.10.1, FLT 1, FLT, Flt-1, FLT1, Fms like tyrosine kinase 1, Fms related tyrosine kinase 1, Fms related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), Fms related tyrosine kinase 1 vascular endothelial growth factor/vascular permeability factor receptor, Fms-like tyrosine kinase 1, FRT, Soluble VEGF receptor 1 14, Soluble VEGFR1 variant 2, Soluble VEGFR1 variant 21, Tyrosine protein kinase FRT, Tyrosine protein kinase receptor FLT, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular endothelial growth factor receptor 1, Vascular endothelial growth factor vascular permeability factor receptor, Vascular permeability factor receptor 1, Vascular permeability factor receptor, VEGFR 1, VEGFR-1, VEGFR1, VGFR1,

Immunogen: peptide

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Peptide affinity purified

Pathway: