Vigabatrin | B2983

Vigabatrin (VGB) is a structural analogue of gamma-aminobutyric acid (GABA) that irreversibly inhibits GABA-transaminase (GABA-T). It inhibits the catabolism of GABA by GABA transaminase and increases GABA levels in the brain. Focal drug delivery into the subthalamic nucleus is beneficial in epilepsy and shows lesser side effects.

Vigabatrin (VGB) is a structural analogue of gamma-aminobutyric acid (GABA) that irreversibly inhibits GABA-transaminase (GABA-T). It inhibits the catabolism of GABA by GABA transaminase and increases GABA levels in the brain. Focal drug delivery into the subthalamic nucleus is beneficial in epilepsy and shows lesser side effects.

B2983 | Vigabatrin DataSheet

Alternate Name/Synonyms: 4-aminohex-5-enoic acid; γ-Vinyl GABA; γ-Vinyl-γ-Aminobutyric Acid; Vigabatrine; Sabril; Sabrilex; GABA Transaminase Inhibitor

Appearance: Solid

Formulation:

CAS Number: 68506-86-5, 60643-86-9

Structure Available?: True

Peptide sequence:

Salt Form: false

Molecular Formula: C₆H₁₁NO₂

Molecular Weight: 129.16

Cell-Permeable?: false

Purity: 98%

Solubilities: ~10 mg/ml in PBS, pH 7.2

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: An irreversible inhibitor of GABA Transaminase

MDL Number:

PubChem CID: 5665

SMILES: C=CC(CCC(=O)O)N

InChi: InChI=1S/C6H11NO2/c1-2-5(7)3-4-6(8)9/h2,5H,1,3-4,7H2,(H,8,9)

InChi Key: