Vildagliptin | 2188

An antidiabetic agent. A potent inhibitor of dipeptidyl peptidase IV (DPP IV), an enzyme that breaks down Glucagon-like peptide 1 (GLP-1). By delaying the degradation of GLP-1, vildagliptin extends the action of insulin while also suppressing the release of glucagon. This leads to a reduction in elevated blood glucose levels (hyperglycemia), which is a characteristic feature of type 2 diabetes.

Vildagliptin is an antidiabetic agent and a potent inhibitor of dipeptidyl peptidase IV (DPP IV), an enzyme that breaks down Glucagon-like peptide 1 (GLP-1).

2188 | Vildagliptin DataSheet

Alternate Name/Synonyms: (S)-1-[N-(3-hydroxy-1-adamantyl)glycyl]pyrrolidine-2-carbonitrile

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 274901-16-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₇H₂₅N₃O₂

Molecular Weight: 303.4

Cell-Permeable?: Yes

Purity: ≥98%

Solubilities: DMSO or H₂O

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A potent DPP IV Inhibitor,

MDL Number: MFCD08275142

PubChem CID: 6918537

SMILES: C1CC(N(C1)C(=O)CNC23CC4CC(C2)CC(C4)(C3)O)C#N

InChi: InChI=1S/C17H25N3O2/c18-9-14-2-1-3-20(14)15(21)10-19-16-5-12-4-13(6-16)8-17(22,7-12)11-16/h12-14,19,22H,1-8,10-11H2/t12?,13?,14-,16?,17?/m0/s1

InChi Key: SYOKIDBDQMKNDQ-XWTIBIIYSA-N