Vimentin Mouse monoclonal Antibody | MB9006

Vimentin Mouse monoclonal Antibody | MB9006 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human,mouse,rat

Application: WB ICC IHC FC

Application Range: WB: 1:2000-1:5000 ICC: 1:200 IHC: 1:200 FC: 1:50-1:100

Background: Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. Intermediate filaments are constructed from two-chain, α-helical, coiled-coil molecules arranged on an imperfect helical lattice and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. One such intermediate filament protein, Vimentin, is a general marker of cells originating in the mesenchyme. Vimentin is frequently coexpressed with other members of the intermediate filament family, such as the cytokeratins, in neoplasms including melanoma and breast carcinoma.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of Vimentin and does not cross-react with related proteins.

Molecular Weight: ~ 54 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Vimentin; VIM

Immunogen: This Antibody is produced by immunizing mice with a synthetic peptide (KLH-coupled) corresponding to a region of Vimentin.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Protein A affinity purified

Pathway: Adherens Junction signaling,