VK3-OCH3 | 2694

VK3-OCH3 is a Vitamin K3 (Menadione) analog that displays potent antitumor activity. It has been shown to induce G2/M arrest and apoptosis in neuroblastoma cells with much less cytotoxicity towards normal cells. VK3-OCH3 is believed to act through up-regulation of heme oxygenase (HO)-1.

VK3-OCH3 is a Vitamin K3 (Menadione) analog that displays potent antitumor activity. It has been shown to induce G2/M arrest and apoptosis in neuroblastoma cells with much less cytotoxicity towards normal cells. VK3-OCH3 is believed to act through up-regulation of heme oxygenase (HO)-1.

2694 | VK3-OCH3 DataSheet

Alternate Name/Synonyms: 2-[(2-Methoxyethyl)thio]-3-methyl-1,4-naphthalenedione; VK3-OMe

Appearance: Light orange to dark orange solid

Formulation: N/A

CAS Number: 255906-59-3

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₄H₁₄O₃S

Molecular Weight: 262.32

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~10 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent antitumor agent

MDL Number: MFCD22575003

PubChem CID: 9903359

SMILES: CC1=C(C(=O)C2=CC=CC=C2C1=O)SCCOC

InChi: InChI=1S/C14H14O3S/c1-9-12(15)10-5-3-4-6-11(10)13(16)14(9)18-8-7-17-2/h3-6H,7-8H2,1-2H3

InChi Key: JTCRCMIBIBLUOK-UHFFFAOYSA-N