VMA21 Polyclonal Antibody | E-AB-53204

VMA21 Polyclonal Antibody | E-AB-53204 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: VMA21, Vacuolar ATPase Assembly Factor, Myopathy With Excessive Autophagy Protein, MEAX, XMEA, Vacuolar ATPase Assembly Integral Membrane Protein VMA21, VMA21 Vacuolar H+-ATPase Homolog (S. Cerevisiae), Myopathy With Excessive Autophagy, VMA21 Vacuolar H+-ATPase Homolo.

Application: IHC, IF, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cell Biology, Signal Transduction

Background: This gene encodes a chaperone for assembly of lysosomal vacuolar ATPase. Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum. Associates with the V0 complex of the vacuolar ATPase (V-ATPase). MEAX is a childhood-onset disease characterized by progressive vacuolation and atrophy of skeletal muscle. It is inherited in recessive fashion, affecting boys and sparing carrier females. Onset is in childhood, and patients exhibit weakness of the proximal muscles of the lower extremities, progressing slowly to involve other skeletal muscle groups over time.

Concentration: 2.6 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human VMA21

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:150-1:500, IF 1: 50-1:200, ELISA 1:5000-1:240000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A