Description
VU-0364439 is a potent positive allosteric modulator (PAM) of mGluR-4 (metabotropic glutamate receptor) (EC₅₀ = 19.8 nM in vitro for human mGluR-4).
VU-0364439 is a potent positive allosteric modulator (PAM) of mGluR-4 (metabotropic glutamate receptor) (EC₅₀ = 19.8 nM in vitro for human mGluR-4).
Alternate Name/Synonyms: N-[3-Chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]-2-pyridinecarboxamide
Appearance: Off-white solid
Formulation: N/A
CAS Number: 1246086-78-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₈H₁₃Cl₂N₃O₃S
Molecular Weight: 422.29
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (~40 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent positive allosteric modulator (PAM) of mGluR-4 (metabotropic glutamate receptor)
MDL Number: N/A
PubChem CID: 46934289
SMILES: C1=CC=C(C(=C1)NS(=O)(=O)C2=C(C=C(C=C2)NC(=O)C3=CC=CC=N3)Cl)Cl
InChi: InChI=1S/C18H13Cl2N3O3S/c19-13-5-1-2-6-15(13)23-27(25,26)17-9-8-12(11-14(17)20)22-18(24)16-7-3-4-10-21-16/h1-11,23H,(H,22,24)
InChi Key: IXHCGJXBIHHIEF-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |