WDR43 Antibody (C-term) [APR32162G]

WDR43 Antibody (C-term) [APR32162G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This WDR43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 636-665 amino acids from the C-terminal region of human WDR43.

Cellular Localisation: Nucleus, nucleolus. Nucleus, nucleolus fibrillar center. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q6ZQL4}

Molecular Weight: 74891

Clone: Polyclonal

Gene Name: WDR43

Gene ID: 23160

Function: Ribosome biogenesis factor that coordinates hyperactive transcription and ribogenesis (PubMed:17699751) . Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I (PubMed:17699751) . Essential for stem cell pluripotency and embryonic development. In the nucleoplasm, recruited by promoter-associated/nascent transcripts and transcription to active promoters where it facilitates releases of elongation factor P-TEFb and paused RNA polymerase II to allow transcription elongation and maintain high-level expression of its targets genes (By similarity) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P, FC

Dilution: WB--1:1000 IHC-P--1:100~500 FC--1:10~50

Synonyms: WD repeat-containing protein 43, WDR43, KIAA0007, UTP5