LBD
WDR43 Antibody (C-term) [APR32162G]
- SKU:
- LBD-APR32162G
- Availability:
- Usually ships in 5 working days
Description
WDR43 Antibody (C-term) [APR32162G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This WDR43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 636-665 amino acids from the C-terminal region of human WDR43.
Cellular Localisation: Nucleus, nucleolus. Nucleus, nucleolus fibrillar center. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q6ZQL4}
Molecular Weight: 74891
Clone: Polyclonal
Gene Name: WDR43
Gene ID: 23160
Function: Ribosome biogenesis factor that coordinates hyperactive transcription and ribogenesis (PubMed:17699751) . Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I (PubMed:17699751) . Essential for stem cell pluripotency and embryonic development. In the nucleoplasm, recruited by promoter-associated/nascent transcripts and transcription to active promoters where it facilitates releases of elongation factor P-TEFb and paused RNA polymerase II to allow transcription elongation and maintain high-level expression of its targets genes (By similarity) .
Summary: N/A
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P, FC
Dilution: WB--1:1000 IHC-P--1:100~500 FC--1:10~50
Synonyms: WD repeat-containing protein 43, WDR43, KIAA0007, UTP5