WDSUB1 Polyclonal Antibody | E-AB-53557

WDSUB1 Polyclonal Antibody | E-AB-53557 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 1700048E19Rik, 2610014F08Rik, FLJ36175, MGC108920, UBOX6 , WD repeat, SAM and U box domain containing protein 1, WD repeat, SAM and U-box domain containing 1, WD repeat, sterile alpha motif and U box domain containing 1 , WDSAM1 , WDSUB1

Application: WB, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cell Biology

Background: WDSUB1 (WD repeat, SAM and U-box domain-containing protein 1), also known as UBOX6 or WDSAM1, is a 476 amino acid protein that contains one SAM (sterile alpha motif) domain, one U-box domain and seven WD repeats. Existing as two isoforms due to alternative splicing, WDSUB1 is encoded by a gene located on chromosome 2. The second largest human chromosome, chromosome 2 encodes over 1, 400 genes and comprises nearly 8% of the human genome, housing a number of disease-associated genes. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alstrm syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.

Concentration: 0.7 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human WDSUB1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 53 kDa

Molecular Weight(Observed): Refer to figures