Description
WNK4 Polyclonal Antibody | E-AB-19365 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: PHA 2B, PHA2B, PRKWNK 4, PRKWNK4, Protein kinase lysine deficient 4, Protein kinase lysine-deficient 4, Protein kinase with no lysine 4, Serine/threonine protein kinase WNK4, Serine/threonine-protein kinase WNK4, WNK lysine deficient protein kinase 4, Wnk4, WNK4
Application: IHC, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Signal transduction
Background: This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.
Concentration: 1.32 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human WNK4
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A