WNT10B Antibody (Center) [APR32308G]

WNT10B Antibody (Center) [APR32308G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, Rat

Specificity: This WNT10B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-222 amino acids from the Central region of human WNT10B.

Cellular Localisation: Secreted, extracellular space, extracellular matrix. Secreted

Molecular Weight: 43000

Clone: Polyclonal

Gene Name: WNT10B

Gene ID: 7480

Function: Member of the Wnt ligand gene family that encodes for secreted proteins, which activate the Wnt signaling cascade. Specifically activates canonical Wnt/beta-catenin signaling and thus triggers beta-catenin/LEF/TCF-mediated transcriptional programs. Involved in signaling networks controlling stemness, pluripotency and cell fate decisions. Acts in the immune system, mammary gland, adipose tissue, bone and skin.

Summary: Tissue Location: Detected in most adult tissues. Highest levels were found in heart and skeletal muscle. Low levels are found in brain

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P, FC

Dilution: WB--1:2000

Synonyms: Protein Wnt-10b, Protein Wnt-12, WNT10B, WNT12