WNT6 Antibody (Center) [APR04116G]

WNT6 Antibody (Center) [APR04116G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This WNT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 173-201 amino acids from the Central region of human WNT6.

Cellular Localisation: Secreted, extracellular space, extracellular matrix

Molecular Weight: 39721

Clone: Polyclonal

Gene Name: WNT6

Gene ID: 7475

Function: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Together with CAV1 may promote chemoresistance of gastric cancer cells to DNA- damaging anthracycline drugs through the activation of the canonical Wnt receptor signaling pathway.

Summary: Tissue Location: Expressed in gastric cancer cell lines and gastric cancer tissues (at protein level) . Detected in the apical gland region of the gastric foveolar epithelium (at protein level)

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Protein Wnt-6, WNT6