26
Wortmannin, Penicillium funiculosum | 1670
- SKU:
- 26-1670-GEN
- Availability:
- Usually shipped in 5 working days
Description
Potent, selective, cell-permeable and irreversible inhibitor of phosphatidylinositol 3-kinase (PI 3-kinase) (IC₅₀ = 2-4 nM). Also potently inhibits polo-like kinase 1 (PLK1) (IC₅₀ = 5.8 nM).
Wortmannin is a potent, selective, cell-permeable and irreversible inhibitor of phosphatidylinositol 3-kinase (PI 3-kinase) (IC₅₀ = 2-4 nM). Also potently inhibits polo-like kinase 1 (PLK1) (IC₅₀ = 5.8 nM).
1670 | Wortmannin, Penicillium funiculosum DataSheet
Alternate Name/Synonyms: KY 12420
Appearance: Off-white solid
Formulation: N/A
CAS Number: 19545-26-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₃H₂₄O₈
Molecular Weight: 428.44
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (50 mM) or EtOH (5 mM)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A PI3 Kinase inhibitor
MDL Number: MFCD00133927
PubChem CID: 312145
SMILES: CC(=O)OC1CC2(C(CCC2=O)C3=C1C4(C(OC(=O)C5=COC(=C54)C3=O)COC)C)C
InChi: InChI=1S/C23H24O8/c1-10(24)30-13-7-22(2)12(5-6-14(22)25)16-18(13)23(3)15(9-28-4)31-21(27)11-8-29-20(17(11)23)19(16)26/h8,12-13,15H,5-7,9H2,1-4H3/t12-,13+,15+,22-,23-/m0/s1
InChi Key: QDLHCMPXEPAAMD-QAIWCSMKSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24 months |