XPC Polyclonal Antibody | E-AB-53352

XPC Polyclonal Antibody | E-AB-53352 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: DNA repair protein complementing XP C cells, DNA repair protein complementing XP-C cells, DNA repair protein complementing XPC cells , p125, RAD4, Xeroderma pigmentosum complementation group C, Xeroderma pigmentosum group C complementing protein, Xeroderma pigmentosum group C protein, Xeroderma pigmentosum group C-complementing protein, Xeroderma pigmentosum group III, XP 3, XP C, XP group C, XP3, Xpc, XPC gene, XPC, XPCC

Application: IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Epigenetics and Nuclear Signaling

Background: The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.

Concentration: 0.66 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human XPC

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A