Description
XPC Polyclonal Antibody | E-AB-53352 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: DNA repair protein complementing XP C cells, DNA repair protein complementing XP-C cells, DNA repair protein complementing XPC cells , p125, RAD4, Xeroderma pigmentosum complementation group C, Xeroderma pigmentosum group C complementing protein, Xeroderma pigmentosum group C protein, Xeroderma pigmentosum group C-complementing protein, Xeroderma pigmentosum group III, XP 3, XP C, XP group C, XP3, Xpc, XPC gene, XPC, XPCC
Application: IHC, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Epigenetics and Nuclear Signaling
Background: The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
Concentration: 0.66 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human XPC
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A