XY1 | B2850

XY1 is an inactive control of SGC707. SGC707 is a potent, selective and allosteric inhibitor of Protein arginine methyltransferase3 (PRMT3) with an IC₅₀ of 31 nM. It inhibits the methylation of histones in cells at a concentration of 1 µM. XY1 is an analog of SGC707 that is completely inactive against PRMT3 at concentrations as high as 100 µM.

XY1 is an inactive control of SGC707. SGC707 is a potent, selective and allosteric inhibitor of Protein arginine methyltransferase3 (PRMT3) with an IC₅₀ of 31 nM. It inhibits the methylation of histones in cells at a concentration of 1 µM. XY1 is an analog of SGC707 that is completely inactive against PRMT3 at concentrations as high as 100 µM.

B2850 | XY1 DataSheet

Alternate Name/Synonyms: 1-naphthalen-2-yl-3-(2-oxo-2-pyrrolidin-1-ylethyl)urea; N-2-Naphthalenyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]urea

Appearance: A crystalline solid

Formulation:

CAS Number: 1624117-53-8

Structure Available?: True

Peptide sequence:

Salt Form: false

Molecular Formula: C₁₇H₁₉N₃O₂

Molecular Weight: 297.35

Cell-Permeable?: True

Purity: ≥98%

Solubilities: ~10 mg/ml in DMF in 0, ~25 mg/ml in in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: An inactive control of SGC707

MDL Number:

PubChem CID: 78871801

SMILES: C1CCN(C1)C(=O)CNC(=O)NC2=CC3=CC=CC=C3C=C2

InChi: InChI=1S/C17H19N3O2/c21-16(20-9-3-4-10-20)12-18-17(22)19-15-8-7-13-5-1-2-6-14(13)11-15/h1-2,5-8,11H,3-4,9-10,12H2,(H2,18,19,22)

InChi Key: GSQHGSRPQHBTTP-UHFFFAOYSA-N