Description
XY1 is an inactive control of SGC707. SGC707 is a potent, selective and allosteric inhibitor of Protein arginine methyltransferase3 (PRMT3) with an IC₅₀ of 31 nM. It inhibits the methylation of histones in cells at a concentration of 1 µM. XY1 is an analog of SGC707 that is completely inactive against PRMT3 at concentrations as high as 100 µM.
XY1 is an inactive control of SGC707. SGC707 is a potent, selective and allosteric inhibitor of Protein arginine methyltransferase3 (PRMT3) with an IC₅₀ of 31 nM. It inhibits the methylation of histones in cells at a concentration of 1 µM. XY1 is an analog of SGC707 that is completely inactive against PRMT3 at concentrations as high as 100 µM.
Alternate Name/Synonyms: 1-naphthalen-2-yl-3-(2-oxo-2-pyrrolidin-1-ylethyl)urea; N-2-Naphthalenyl-N'-[2-oxo-2-(1-pyrrolidinyl)ethyl]urea
Appearance: A crystalline solid
Formulation:
CAS Number: 1624117-53-8
Structure Available?: True
Peptide sequence:
Salt Form: false
Molecular Formula: C₁₇H₁₉N₃O₂
Molecular Weight: 297.35
Cell-Permeable?: True
Purity: ≥98%
Solubilities: ~10 mg/ml in DMF in 0, ~25 mg/ml in in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: An inactive control of SGC707
MDL Number:
PubChem CID: 78871801
SMILES: C1CCN(C1)C(=O)CNC(=O)NC2=CC3=CC=CC=C3C=C2
InChi: InChI=1S/C17H19N3O2/c21-16(20-9-3-4-10-20)12-18-17(22)19-15-8-7-13-5-1-2-6-14(13)11-15/h1-2,5-8,11H,3-4,9-10,12H2,(H2,18,19,22)
InChi Key: GSQHGSRPQHBTTP-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
RT |
Shelf Life: |
36 months |