YAF2 polyclonal Antibody | BS60278

YAF2 polyclonal Antibody | BS60278 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Members of the myeloctyomatosis viral oncogene homologue (Myc) family, which include c-Myc, N-Myc and L-Myc, encode transcription factors that play a role in the acceleration of cell cycle progression and cell growth, inhibition of cell differentiation, and initiation of programmed cell death (apoptosis) . YY1-associated factor 2, also known as YAF2, is a 180 amino acid protein that binds to c-Myc and inhibits c-Myc-mediated pathways. It also binds to N-Myc, enhancing N-Myc-dependent transcriptional activation. Furthermore, YAF2 interacts with YY1 to antagonize YY1 transactivation of muscle-specific promoters. Localized to the nucleus, YAF2 contains an N-terminal C2-X10-C2 zinc finger and exists as two isoforms.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: YAF2 polyclonal Antibody detects endogenous levels of YAF2 protein.

Molecular Weight: ~ 20 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: YY1-associated factor 2; YAF2

Immunogen: A synthetic peptide corresponding to residues in Human YAF2.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: